Higher Scientific Officer - Cell Biology / Immuno-Oncology Drug Discovery (ID235)

Salary: Commencement on the salary range is subject to comparable skills and experience. Future progression is based on annual performance review.

Duration of Contract: Fixed Term initially for 2 years with possibility for extension

Hours per week: 35 hours per week (Full Time)

Closing Date:  5th June 2022

Summary of Role

We are looking for a cell biologist to join one of our drug discovery teams in the Cancer Therapeutics Unit. The team's current research is largely focussed on the design and application of small molecules in immuno-oncology, which seeks to harness the body’s own immune system to destroy cancer cells. The current project is exploring ways to modulate MHC-I antigen presentation in order to re-engage the immune system within the tumour microenvironment.

As a Higher Scientific Officer you will be required to design and perform a range of cellular assays to investigate the effects of our small molecule inhibitors on both antigen presentation and immune cell activation. You will also be required to design and execute experiments using molecular biology techniques to modulate activity and/or expression of target proteins. You will be working as part of a multi-disciplinary team.

Key Requirements

The successful candidate must have experience in cell biology with either a PhD in biological sciences or several years cell biology experience post completion of a first degree. Good communication skills and an ability to work as part of a team are essential.

Department/Directorate Information

The Cancer Therapeutics Unit is a major component of the Division of Cancer Therapeutics and is a multidisciplinary 'bench to bedside' centre, comprising approximately 160 scientists dedicated to the discovery and development of novel therapeutics for the treatment of cancer. We implement innovative drug discovery technologies, discover novel mechanism-based drugs, and develop these as rapidly as possible from the laboratory through to hypothesis-testing early clinical trials. These activities are carried out in highly focused multi-disciplinary project teams analogous to those in a biotechnology company, with patient benefit as the primary driver. We publish our work extensively and have a large network of collaborations with academia, biotechnology companies, and the pharmaceutical industry. 

We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Esther Arwert via email at esther.arwert@icr.ac.uk

Why work for us?

As a member of staff, you'll have exclusive access to a range of staff benefits.

The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.

We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.