LocationLocation:
Sutton (Greater London)
DepartmentDepartment:
Cancer Therapeutics
Salary Details:Salary Details:
Salary Range: £28,500 - £39,000 per annum
Contract:Contract:
Fixed term
External Advertising End Date
02 Oct 2023

Key Information

Salary: Scientific Officer salary range: £28,500 - £30,000, Higher Scientific Officer salary range: £37,050 - £39,000. Commencement on the salary range is subject to comparable skills and experience. Future progression is based on annual performance review.

 
This role is eligible for ICR Sponsorship. Support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here
 

Duration of Contract: Fixed Term for 2 years

Hours per week: 35 hours per week (Full Time)

Closing DateMonday 2nd October 2023

Interviews: Wednesday 11th October 2023

Job Details

Under the leadership of Olivia Rossanese, we are seeking to appoint a Scientific Officer or Higher Scientific Officer to join the Centre for Target Validation to carry out lab-based cell biology research focused on potential therapeutic targets in cancer. Projects will involve the use of genetic techniques (RNAi/CRISPR), targeted protein degradation, tool compounds and molecular biology to generate key decision-making data in target validation and enable target prioritisation for drug discovery. The post holder will also contribute to assay development and biomarker discovery for targets that move to a drug discovery phase within the ICR’s Centre for Cancer Drug Discovery. This position is offered on a 2 year fixed-term contract in the first instance.

Key Requirements

The successful candidate must have:

  • Knowledge and experience in lab-based cell biology research 
  • Knowledge of cancer biology 
  • Knowledge of experimental approaches to therapeutic target validation in cancer
  • Skills in cell biology techniques used for target validation (e.g. RNAi, CRISPR, biomarker detection, viral transduction)
  • Strong written and oral communication skills
  • Strong interpersonal skills with proven ability to collaborate with scientists from other disciplines
  • Excellent record keeping skills
  • Proactive approach with excellent time management skills
  • High motivation and a strong desire to achieve scientific excellence, prioritising quality and reproducibility of results
  • Experience working in lab-based cell biology (which can include PhD if applicable). At least three years of lab experience for Higher Scientific Officer.

  

Department/Directorate Information

Centre for Target Validation
The ICR has established a Centre for Target Validation that will accelerate the translation of ICR and collaborator research into drug discovery programmes. The Centre will deliver bespoke, hypothesis-driven data packages to support decision-making for launch of a drug discovery project. The Centre’s dedicated resources, including biology, functional genomics, assay sciences, chemistry, and bioinformatics teams, will support joint project teams that combine the deep biological and therapeutic knowledge of ICR investigators with the validation and technical expertise of drug discovery scientists. Scientists in the Centre for Target Validation will work closely with colleagues in the ICR’s Centre for Protein Degradation to exploit emerging technology and protein degradation tools for robust target validation experiments. The Centre for Target Validation will serve as a hub, connecting researchers to expertise and resources that will validate and streamline robust, targets into drug discovery programmes in the ICR’s Centre for Cancer Drug Discovery or into collaborative programmes with external commercial therapy discovery partners.
 
Centre for Cancer Drug Discovery, Division of Cancer Therapeutics  
The Centre for Cancer Drug Discovery (CCDD), within the Division of Cancer Therapeutics (DCT), is a multidisciplinary 'bench to bedside' centre, comprising around 200 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The CCDD’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible. Our world-class biologists, chemists and drug metabolism specialists work together focusing on new molecular targets emerging from human genome and ground-breaking cell biology research. This is an exciting and fast-moving cancer research setup and offers the opportunity to work within a multi-disciplinary environment using state-of-the-art techniques and equipment.
 

We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Dr Olivia Rossanese ([email protected]) or Dr Michael Bright ([email protected]) via Email.

About The Institute of Cancer Research

Why work for us?

As a member of staff, you'll have exclusive access to a range of staff benefits.

The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.

 

We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.

Other jobs like this

Location
Sutton (Greater London)
Department
Cancer Therapeutics
Salary Details:
Salary Range: £28,500 - £39,000 per annum
Contract:
Fixed term
External Advertising End Date
02 Oct 2023
Location
Sutton (Greater London)
Department
Cancer Therapeutics
Salary Details:
Salary Range: £47,500 - £50,000 per annum
Contract:
Permanent
External Advertising End Date
10 Oct 2023
Similar

Data Scientist

Location
Sutton (Greater London)
Department
Cancer Therapeutics
Salary Details:
Salary Range: £50,000 - £57,680 per annum
Contract:
Fixed term
External Advertising End Date
09 Oct 2023