LocationLocation:
Sutton (Greater London)
DepartmentDepartment:
Cancer Therapeutics
Contract:Contract:
Permanent
External Advertising End Date
25 Feb 2024

Key Information

Salary: Subject to comparable skills and experience. Future progression is based on annual performance review.
 
This role is eligible for ICR Sponsorship.  Support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here.
 

Job Details

Under the leadership of the Director of the Centre for Protein Degradation, we are seeking to appoint a Staff Scientist or Senior Staff Scientist to lead the conception and delivery of biology components of Centre projects, including through their own research contributions. Projects will involve the coordination of research to evaluate new degradation approaches, establishing relevant assays for small molecule degraders, and applying chemical and biological targeted protein degradation technologies to new drug target validation. To support these aims, the post holder will supervise a small group of biology scientists dedicated to the Centre’s projects. The post holder will play a key role in establishing and supporting collaborative protein degradation projects across ICR, including coordinating proteomics experiments in collaboration with the ICR Functional Proteomics Group. The post holder will work closely with the computational biology team in the Centre for Cancer Drug Discovery to analyse biological datasets from profiled compounds and targeted degradation experiments, to prioritize new drug discovery targets.

Key Requirements

The successful candidate will have the skills and expertise to lead the biology aspects of collaborative multi-disciplinary research projects within the Centre for Protein Degradation. 

Department/Directorate Information

Scientists in the Centre for Cancer Drug Discovery implement innovative drug discovery technologies, discover novel mechanism-based drugs, and develop these as rapidly as possible from the laboratory through to hypothesis-testing early clinical trials. We publish our work extensively and have a large network of collaborations with academia, biotechnology companies, and the pharmaceutical industry. Our drug discovery Biology teams are dedicated to translational and drug discovery research, applying molecular pharmacology and cancer biology approaches to explore the therapeutic potential of new targets, and implementing functional and mechanistic assays to support progression of new small molecule therapeutics.

Based within the ICR Centre for Cancer Drug Discovery, the Centre for Protein Degradation's scientists apply a wide range of protein degradation technologies to benefit fundamental discovery science and translational research across the ICR. This research provides a nucleus for other teams to collaborate with, bringing their specialist biological and clinical knowledge to enable the exploration of therapeutic protein degradation for cancer patient benefit.
   

Applications
We encourage all applicants to access the job pack attached for more detailed information regarding this role. Applications for this role are being processed by the recruitment agency Skills Alliance.

If you would like to apply for this role, please get in touch with Aisling O’Halloran at [email protected] or on 0207 220 6206. Applications received through the ICR website will not be considered.

*Please note applications will be viewed on receipt; we reserve the right to close the role.

About The Institute of Cancer Research

Why work for us?

As a member of staff, you'll have exclusive access to a range of staff benefits.

The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.

We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.

 

 

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