Postdoctoral Training Fellow - Innate Immune Responses to Genome Instability

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Location:

Chelsea

Department:

Genome Stability and Innate Immunity

Salary Details:

Salary Range: £35,844 - £48,224 per annum

Contract:

Fixed term

Contract Length:

Not Specified

Advertising End Date:

27 Oct 2024

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Postdoctoral Training Fellow - Innate Immune Responses to Genome Instability

Key Information

Salary: Dependent on relevant Postdoctoral experience. Future progression is based on annual performance review. If the candidate has completed their viva but has not yet been awarded their PhD, the starting salary will be £35,844, pre-PhD level. Progression to the full PDTF scale will commence once confirmation of PhD award is received. Award must be provided within 6 months of start date.

This role is eligible for ICR Sponsorship. Support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here.

Duration of Contract: Fixed Term until 31 March 2027

Hours per week: 35 hours per week (Full Time)

Closing Date: 27th October 2024

Job Details

Under the leadership of Dr Christian Zierhut, we are seeking to appoint a Cancer Research UK-funded Postdoctoral Training Fellow to develop an exciting research project to determine how innate immune signalling is activated by genome instability, and how it can be exploited for cancer therapy. Several projects are currently available.

For general information on Post Doc's at The ICR can be found here.

Key Requirements

The successful candidate must have relevant technical experience with automated microscopy and image analysis, genomic analysis, or murine models of cancer. Experience in innate immunity and/or genome instability research is desirable. The successful candidate will have intellectual freedom in developing this project, with support from the Group Leader, whilst working as part of a collaborative and multi-disciplinary team. Although the position is currently funded until 31 March 2027, there is potential for further extension.

The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 10 years

Genome Stability and Innate Immunity Group, Division of Cancer Biology, Chelsea, London

The Genome Stability and Innate Immunity Group, led by Dr Christian Zierhut, seeks to understand how innate immune responses are activated during genotoxic stress, and to establish how these collaborate with other signalling to regulate cell fate during genotoxic stress. Ultimately, we aim to develop rule sets for how cell fates are decided during genotoxic stress, which we hope will support cancer therapy. We employ a multi-disciplinary approach that combines state of the art cell biology, microscopy, genetic screening, biochemistry and structural biology techniques.

Our team is embedded within the Cancer Biology Division at the ICR’s Chester Beatty Laboratories in Chelsea, London. We have a highly supportive and interactive research environment, and state of the art facilities for cell biology, molecular biology, next-generation sequencing and structural biology. We also closely interact with other divisions at the ICR, including Breast Cancer Research, Radiotherapy and Imaging, and Structural Biology. The great variety of disciplines at the ICR will ensure that the successful candidate will be exposed to fantastic research and seminars from all types of backgrounds.

We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Dr Christian Zierhut by emailing [email protected].

About The Institute of Cancer Research

Why work for us?

As a member of staff, you'll have exclusive access to a range of staff benefits.

The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.

We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.

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