The Institute of Cancer Research is looking for a Clinical Data Analyst to work in the Investigator Initiated Trials (IIT) Team, which is part of the Drug Development Unit (DDU). The post offers an enthusiastic and well-motivated individual a chance to work in a motivated and supportive academic team that are at the forefront of Phase-I cancer trials.
Department/Directorate Information
The Drug Development Unit, within the ICR and Royal Marsden, is a dedicated Clinical Trials Unit, with bespoke facilities to conduct early phase clinical trials. The Unit, led by Professor Johann de Bono, comprises Drug Development Unit – Investigator Initiated Trials team which aims to seamlessly integrate preclinical drug discovery, proof-of-principle phase I trials and tumour-specific evaluation of novel agents. It is a conduit for the two-way communication between laboratory and clinical teams that is so essential for successful modern drug development.
The unit conducts first-in-man phase I trials involving a range of targets, including growth factor or intracellular signalling, angiogenesis, apoptosis, epigenetics and DNA repair. All trials are underpinned by extensive analysis of biomarkers, both predictive and pharmacodynamics. The DDU includes The Oak Foundation Drug Development Centre (Oak Ward) housed within The Royal Marsden at the Sutton site and specifically designed for phase I clinical trials. Opened in February 2005, the centre provides 10 inpatient beds, five treatment chairs and two outpatient suites, and allows researchers to enter almost 300 patients onto phase I trials each year. This makes the unit one of the largest of its kind in the world.
The DDU also has a portfolio of investigator-initiated phase 1 trials (IIT’s) of novel targeted agents and combinations of these, including those made available via Cancer Research-UK’s (CRUK) Experimental Cancer Medicine Centres (ECMC) Combinations Alliance. These studies are centrally managed by the IIT team within the DDU that performs those functions associated with sponsoring early phase trials including project management, monitoring, pharmacovigilance, database development and central data review. The successful applicant will support the Senior Clinical Data Analyst in overseeing data management activities of the IIT team.
Summary of Role
The post holder will be responsible for managing the data collected during a clinical trial. This will include designing the database used to collect the data, reviewing the data that is collected, and analysing the data by creating data tables for reports and publications. The role will also involve supporting the Senior Clinical Data Analyst in overseeing data management activities of the IIT team. This role is office based with some flexibility.
Key Requirements
We are looking for an individual with a passion for data and enthusiasm to fit into a forward thinking Phase I team, working on novel approaches to cancer treatments. The successful candidate must be educated to a degree level in life science or nursing. They should have excellent interpersonal skills and the ability to prioritise and manage workload as an essential skill. It is also desirable that the applicant has knowledge of clinical trials or oncology, and has an understanding of ICH-GCP (Directive 2001/20/EC and 2005/28/EC).
We encourage all applicants to access the job pack attached for more detailed information regarding this role.
Additional Information
Appointments will be on a one-year contract in the first instance. To apply for this post, please submit an online application including a supporting statement, detailing reasons why you are applying for the post and attach your CV.
Due to the high volumes of applications we receive, we reserve the right to close the advert before the published closing date once we have received a sufficient number of applications. Therefore, we advise that you to submit your application, as early as possible to avoid disappointment. For an informal discussion regarding the role, please contact Toby Prout via email on [email protected].