Postdoctoral Training Fellow - Functional Genomics

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Location:

Chelsea

Department:

Functional Genomics

Salary Details:

Salary Range: £45,600 - £49,350 per annum

Contract:

Fixed term

Contract Length:

Not Specified

Advertising End Date:

23 Mar 2025

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Postdoctoral Training Fellow - Functional Genomics

Key Information

Salary: £45,600 - £49,350 p.a. inclusive dependent on relevant Postdoctoral experience. Future progression is based on annual performance review.

This role is eligible for ICR Sponsorship. Support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here.

Duration of Contract: Fixed Term for 3 years in the first instance

Hours per week: 35 hours per week (Full Time)

Location: Chelsea

Closing Date: 23 March 2025

Job Details

Under the guidance of Dr Rachael Natrajan, we are seeking to recruit a Postdoctoral Training Fellow to lead on the biological and mechanistic insights into the evolutionary dynamics of the epigenetic sub-clonal evolution of response to neoadjuvant immunotherapy and chemotherapy in TNBC in vivo mouse models using using high throughput cellular tracking coupled with single cell sequencing and functional genomic screening approaches.

The successful candidate will perform experimental work to identify epigenetic regulators of neoadjuvant immunotherapy and chemotherapy resistance in TNBC and assess the implications of novel biology using innovative in vivo models and developing genetic screening approaches in vitro and in vivo.

About you

The successful candidate must have a PhD in biology, biochemistry, genetics or other associated subjects and have an excellent track record in biomedical research and experience in cell and molecular biology. Experience with in vitro and in vivo cancer models is essential.

For general information on Postdocs at The ICR, more information can be found here.

Department/Directorate Information

The Functional Genomics laboratory headed by Dr Rachael Natrajan is a multidisciplinary dynamic research
group with the mission to develop new treatment strategies for breast cancers resistant to standard therapies. This role will be co-mentored by Dr Esther Arwert, Group Leader Functional Tumour Immunology group.

Both groups sit within the Breast Cancer Now Toby Robins Research Centre, within the Division of Breast Cancer Research at the ICR. The Centre is the first centre in the UK entirely devoted to breast cancer research. Our goal is to advance research into the causes, diagnosis and treatment of breast cancer. It is located in state-of-the-art laboratory space, with excellent core facilities and is funded through a long term renewable programme grant from Breast Cancer Now.

What we offer

A dynamic and supportive research environment
Access to state-of-the-art facilities and professional development opportunities
Collaboration with leading researchers in the field
Competitive salary and pension

We encourage all applicants to access the job pack attached for more detailed information regarding this role.

About The Institute of Cancer Research

Why work for us?

As a member of staff, you'll have exclusive access to a range of staff benefits.

The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.

At the Institute of Cancer Research, we champion diversity as we believe it fuels innovation and drives impactful research. We welcome applicants from all walks of life, valuing diverse perspectives that enrich our work.

Don't let a checklist of qualifications hold you back – if you're passionate about the role, we want to hear from you. Your unique experiences and backgrounds contribute to the richness of our team. We are committed to being an equal opportunity for all, regardless of ethnicity, gender, age, sexual orientation, disability, or any other dimension of diversity. Join us in creating an inclusive environment where everyone's voice is heard and valued.

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