About the role
Under the guidance of Alexis De Haven Brandon, We seek a dedicated early career in vivo scientist. The central aim of this position is to assist in the undertaking of in vivo technical work, playing a key role in supporting a variety of in vivo experiments and laboratory approaches. You will be an in vivo scientist with a basic knowledge and experience of in vivo techniques.
Your responsibilities will include monitoring animal welfare, carrying out animal procedures, maintaining detailed records. This position offers an excellent opportunity for an early career in vivo scientist with a passion for in vivo science, and animal welfare. We offer full training to gain a home office PIL, for more technical procedures to the right candidate.
There will occasionally be the need for out of hours work to ensure Home office compliance, and the needs of the projects are met.
The successful candidate will be a motivated individual with a strong background in animal welfare and husbandry in a research setting.
We highly value diversity and encourage candidates from all backgrounds to apply.
About you
The successful candidate must have:
- Broad-based knowledge of animal welfare within a research setting
- At least a year in an in vivo research setting with rodents.
- Proven experience in husbandry, welfare monitoring and animal handling.
- Ability to work both independently and as part of a team.
- BSc in life sciences/or related degree
- High degree of integrity and understanding of the need for confidentiality surrounding drug discovery programmes.
- Willingness to occasionally work out of hours.
About our team
Under UK law, animals can only be used for research if there is no appropriate alternative. All our research proposals are thoroughly assessed before approval to ensure that there is no alternative to the use of animals, and that the studies will provide valuable information that will ultimately help cancer patients.
The ICR is strongly committed to the highest standards of animal welfare in all research studies, and has led the development of best practice in this area. We also support the principles of the 3Rs – replacement, refinement and reduction of use of animals for research – and are working to develop alternative experimental techniques.
The In Vivo Pharmacology team provides in vivo support for all projects within the Centre for Cancer Drug Discovery. The team carries out critical proof-of-principle intervention studies and provides the essential pharmacological assays required to guide target validation in addition to the optimisation and selection of new drug candidates. Importantly, these experiments include the demonstration of drug effects in vivo, biomarker discovery and therapy studies all of which underpin the drug discovery programs across the portfolio. The team works across a wide range of tumour models, including human tumour xenografts models (both cell line- and patient-derived xenografts), genetically engineered mouse models and organoid based models. The team is also highly experienced in preclinical metastatic models. The team has specialised skills to develop and implement novel models, and supporting the design and implementation of studies, all whilst complying with increasingly complex Home Office regulations.
Department/Directorate Information
About our organisation
We are one of the world’s most influential cancer research institutes with an outstanding record of achievement dating back more than 100 years. We are world leaders in identifying cancer genes, discovering cancer drugs and developing precision radiotherapy. Together with our hospital partner The Royal Marsden, we are rated in the top four centres for cancer research and treatment worldwide. As well as being a world-class institute, we are a college of the University of London. We are consistently in the top performing universities in the league table of university research quality complied from Research Excellence Framework (REF 2014 &2021).
We have charitable status and rely on support from partner organisations, charities, donors and the general public.
We have more than 1000 staff and postgraduate students across three sites – in Chelsea and Sutton.
What we offer
- A dynamic and supportive research environment
- Access to state-of-the-art facilities and professional development opportunities
- Collaboration with leading researchers in the field
- Competitive salary and pension
We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact [email protected]